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alexion

Senior Medical Director, Rare Cancers

Location: Boston, United States Job reference: R-233420 Date posted: 01/05/2026
Typical Accountabilities: • Leads the GMAT for each brand and ensures cross functional membership to drive robust iMAP development in Oncology TA • Develops an iMAP for each assigned brand ensuring that specific annual objectives and milestones are set to enable the achievement of the longer term medical strategy • Serves as Medical Affairs lead on Oncology Global Product Teams (GPTs) and Oncology Global Brand Teams (GBTs) bringing the voice of the patient and physician into the development and commercialisation process • Ensures medical insights from key countries are used to inform all evidence, product development and franchise strategy deliverables • Reviews and provides input for regulatory documents, including Core Data Sheet, Product Labels, Patient Information Leaflets etc. • Reviews and provides input into Global Reimbursement Dossier and Global Value Pack • Builds and leverages relationships with external customers to ensure robust physician and patient insights are built into brand or franchise plans to drive successful product launches • Maintains a good working knowledge of company standards on medicines promotion and supports the Nominated Signatories in ensuring product related materials and activities for external audiences comply with these standards • Initiates and develops relationships with internal and external stakeholders to enhance the scientific and clinical understanding of brands • Ensures scientific publication strategy and content is appropriately aligned with medical affairs strategy • Leads development of the External Scientific Research (ESR) strategy for the assigned late stage development and/or marketed compounds together with the relevant Oncology GMAT(s) and presents to the Oncology GPT(s) for endorsement. • Serves as Medical Affairs lead on the ESR Global Review and Evaluation Group (GREG) as the decision maker on strategic alignment and Global Medical Affairs funding for the approved studies • Partners with Global Medical Information Team to identify content needs for Medical Information, provide access to relevant data, and obtain resource to create and maintain the global medical information content • Develops, gains approval for and manages the annual budget required to deliver the objectives for assigned brand(s) in line with defined processes and policies • Acts an expert author to the Late Stage Target Product Profiles (TPPs), starting 9-12 months before Phase III ID (investment decision) bringing insights from providers, patients and policy makers, knowledge of the patient journey, treatment impact and translation of efficacy to effectiveness • Develops External Scientific Research Areas of Interest and is accountable for review and approval of ESRs that support generation of evidence aligned to science strategy • Works with Medical Excellence leads to plan for development and delivery of necessary internal medical knowledge, skills, and tools to support medical plan execution in the countries/affiliates Typical People Management Responsibility (direct / indirect reports): • Approximate number of people managed in total (all levels) - 0+ What is the global remit? (how many countries will the role operate in?): Education, Qualifications, Skills and Experience: • Essential: Master’s degree in a scientific discipline (MS in Biology, Biochemistry, Chemistry, Nursing, etc.); 6+ years Oncology therapeutic area experience (academic research, clinical or pharma/biotech setting); Extensive experience of Medical Affairs function within a pharmaceutical industry; Extensive experience in relationship and stakeholder management (3P’s: Payer, Provider and Patients); Effective matrix leadership experience; Experience working at the medical marketing interface; Experience in Evidence generation planning and clinical trial design; Financial Management foundation knowledge; Fluency in spoken and written English; A track record of building and maintaining a deep continued connection to medical practice/healthcare delivery; Collaborative/matrix management skills with a focus on leading diverse groups (e.g., cultural, geographical, functional) to achieve excellent results in shared goals; Strong communication skills with the ability to distil complexity down to what matters to our stakeholders; Strong Financial/Budget Management and Project Management skills; Strong business acumen • Desirable: Doctorate degree (MD or equivalent) with Oncology specialization or PhD in Sciences preferred; Extensive knowledge of the latest technical, regulatory, policy and patient–centric developments; Experience delivering country medical affairs plans Key Relationship to reach solutions: • Internal (to AZ or team): Management within Global Medical Affairs; Market Access, Health Economics and Outcomes Research (HEOR), PaCe and Compliance Teams; Regional and Country Medical Affairs teams; GPPS, Sales and Marketing functions • External (to AZ): Oncology Service Providers; Scientific and Patient Experts; Regulatory bodies; Payor/Health Technology Assessment bodies; Scientific and Academic research organisations; Patient organisations; Local or regional stakeholders including policymakers, Healthcare Professionals and their associated professional organisations

Compensation Pay Range:

247,786.40 - 371,679.60 USD Annual

The annual base pay (or hourly rate of compensation) for this position is outlined above. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

05-Jan-2026

Closing Date

29-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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